Late Causes of Death After Congenital Heart Defects
نویسندگان
چکیده
منابع مشابه
Late Causes of Death After Congenital Heart Defects: A Population-Based Study From Finland.
I mprovement in life expectancy of patients with congenital heart disease (CHD) (2,3) has resulted in emergence of a patient population for which there is sparse track record in adult medicine. Tracking these outcomes is fascinating, yet problematic because CHD is not a single disease entity but an infinite combination of structural and physiological variables. As medical and surgical managemen...
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Congenital heart defects (CHDs) are the most common major developmental anomalies and the most frequent cause for perinatal mortality, but their etiology remains often obscure. We identified a locus for CHDs on 6q24-q25. Genotype-phenotype correlations in 12 patients carrying a chromosomal deletion on 6q delineated a critical 850 kb region on 6q25.1 harboring five genes. Bioinformatics prioriti...
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BACKGROUND The long-term impact of surgical correction of congenital heart defects (CHD) on exercise capacity and quality of life (QoL) has not been well established. AIM To evaluate exercise capacity, QoL, physical activity and depression in young adult patients with a history of congenital heart defect surgery (GUCH) for simple left-to-right shunts, and to compare these parameters with thos...
متن کاملSudden unexpected death in children with congenital heart defects.
AIMS Congenital heart defects (CHDs) are the most common birth defects and are an important cause of death in children. The fear of sudden unexpected death has led to restrictions of physical activity and competitive sports. The aim of the present study was to investigate the rate of sudden unexpected deaths unrelated to surgery in children 2-18 years old with CHDs and, secondarily, to determin...
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BACKGROUND Hyaluronan (HA) is required for endothelial-to-mesenchymal transition and normal heart development in the mouse. Heart abnormalities in hyaluronidase 2 (HYAL2)-deficient (Hyal2-/- ) mice and humans suggested removal of HA is also important for normal heart development. We have performed longitudinal studies of heart structure and function in Hyal2-/- mice to determine when, and how, ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2016
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2016.05.037